Answers revealed in the comments.
GAME 1
What well-known author wrote the murder-mystery play The Mousetrap, which opened in London in 1952 and has run continuously since then, making it the longest-running West End show?
GAME 2
Kary Mullis shared the 1993 Nobel Prize in Chemistry for the invention of the PCR technique, which is used to make many copies of a region of DNA. What do any one of the three letters in PCR stand for?