Answers revealed in the comments.
GAME 1
In the 20th century, what Republican lost as a vice presidential candidate and two decades later lost as a presidential candidate, never winning either office?
GAME 2
What city hosts what has been called the second-largest Mardi Gras festival in the U.S. each year in its Soulard neighborhood? The city was originally founded by French fur traders in 1764.
hebspeaks 
game one answer: Bob Dole
game two answer: St. Louis